Ko Chun (Chow Yun-fat) is a world-famous gambler, so renowned and talented at winning various games of chance that he is referred to as the "God Of Gamblers".
Sing finds Michael "Dagger" Chan in order to become Ko Chun's next disciple, but the two must put aside their differences when they discover that a gang boss is bent on ruining the God of Gamblers' name.
Ko Chun is an extremely talented and well known gambler. On the eve of a big confrontation with a famous Singaporean gambler, Ko walks into a trap set by Knife, an avid but a so-so gambler, meant for an Indian neighbour. Struck on the head, Ko suffers from amnesia and regresses to a child-like state. Knife takes care of Ko and begins to exploit Ko's gambling talents.
Sing, a dumb, lovable mainlander with supernatural powers comes to China to visit his uncle Tat. When it's revealed that Sing can see through objects, Tat employs him as "The Saint of Gamblers," and proceeds to set him loose in the gambling world.
Sing and Mei are two siblings with special powers which the former uses to gamble. When both are unavailable, a gangster hires Fanny, a con artist, to compete in a gambling competition.
Ray Thai is the tyrant of gamblers in Macau. He puts forward a masked Saint Of Gamblers to cover for him in the casino. Meanwhile, Uncle Tat has lost his livelihood since the real Saint of Gamblers retired. He sets out in search of the new Saint. He discovers God Bless You, who possesses extraordinary powers and takes him under his wing.