Convict Van Duff engineers a large-scale prison break; the six survivors hide out in a forgotten mine working near the prison, then set out on a long, dangerous journey by foot, car, train and truck to retrieve Duff's bank loot. En route, as they touch the lives of "regular folks," each has his own rendezvous with destiny.
A wide-eyed working girl wins a $5,000 sweepstakes and plunges into the lush life of New York City, where she meets a bellboy who is more than he seems.
Medical intern Robert Morley is distraught after his wife dies in childbirth. He's resentful of his new son and wants nothing to do with him. He leaves the child with his aunt and uncle and heads off to Europe to pursue his medical studies. Morley returns to his hometown six years later, now a successful doctor and engaged to be married to a beautiful socialite. He also feels differently about the boy and attempts to gain custody from his aunt and uncle.
An American woman falls in love with a romantic Parisian head waiter who tries to save her from her possessive wealthy ex-husband who wants to keep her under his control.
Vera Kowalska is put on trial for murdering concert pianist Michael Michailow. In court it is revealed that some years earlier Michael ruined Vera's life.
Pathfinder, a white man raised by the Mohican Indians, joins forces with the British army to avenge himself on the Mingo warriors and the French, who have brought death and pillage to his people. He takes on a mission to retrieve secret plans from within the French fort at St. Vicente.
Quiet, organised Dr Talbot meets nightclub singer Nora Prentiss when she is slightly hurt in a street accident. Despite her misgivings they become heavily involved and Talbot finds he is faced with the choice of leaving Nora or divorcing his wife. When a patient expires in his office, a third option seems to present itself.
