3 South is an American animated series that aired on MTV. The show focused on two lifelong friends, Sanford and Del, and their adventures at the fictional Barder College. With the exception of their roommate Joe, nearly everyone at Barder is stupid and inept. Nonetheless, the idiotic, irresponsible, and thoughtless Sanford and Del are portrayed as the series' heroes, whereas the responsible, intelligent Joe is the de facto villain in most episodes. The series was created by Family Guy veteran writers Mark Hentemann and Steve Callaghan, based on a short film they had created years earlier. It is to-date the only animated series produced for MTV by Warner Bros. Animation. The show's theme song is The Flaming Lips' song "Fight Test" from the album Yoshimi Battles the Pink Robots.

Sick, twisted, politically incorrect and Freakin' Sweet animated series featuring the adventures of the dysfunctional Griffin family. Bumbling Peter and long-suffering Lois have three kids. Stewie (a brilliant but sadistic baby bent on killing his mother and taking over the world), Meg (the oldest, and is the most unpopular girl in town) and Chris (the middle kid, he's not very bright but has a passion for movies). The final member of the family is Brian - a talking dog and much more than a pet, he keeps Stewie in check whilst sipping Martinis and sorting through his own life issues.

The comedy, which takes place in a fictitious desert town near the U.S.-Mexico border, centers on the intertwining daily lives of neighbors Bud Buckwald and Ernesto Gonzales. Bud, a married father of three, is a Border Patrol agent who feels threatened by the cultural changes that have transformed his neighborhood. Living next door is Ernesto, an industrious Mexican immigrant and father of four, who is proud to be making it in America. As Bud and Ernesto’s paths begin to cross, their families become bound by friendship, romance and conflict.

Seth MacFarlane's Cavalcade of Cartoon Comedy is an American cartoon web series created by Seth MacFarlane. The series is based on the cutaway jokes on Family Guy.

The series focuses on an eccentric motley crew that is the Smith family and their three housemates: Father, husband, and breadwinner Stan Smith; his better half housewife, Francine Smith; their college-aged daughter, Hayley Smith; and their high-school-aged son, Steve Smith. Outside of the Smith family, there are three additional main characters, including Hayley's boyfriend turned husband, Jeff Fischer; the family's man-in-a-goldfish-body pet, Klaus; and most notably the family's zany alien, Roger, who is "full of masquerades, brazenness, and shocking antics."