Dr. Frankenstein and his monster both turn out to be alive, not killed as previously believed. Dr. Frankenstein wants to get out of the evil experiment business, but when a mad scientist, Dr. Pretorius, kidnaps his wife, Dr. Frankenstein agrees to help him create a new creature.
Fact and fiction collide in this exploitation flick that employs documentary footage depicting the bizarre self-flagellation rituals of the fanatical Catholic sect known as the Penitentes. Mixed with those truly disturbing sequences is a story concerning a killing in New Mexico, itself inspired by the murder of real-life reporter Carl Taylor as he worked on an article on the Penitentes.