Muriel Flemming secretly marries Graydon Burton before he heads West to make his fortune. Later, when he is about to board a train to return to his wife, he is accused of a murder that was actually committed by crooked attorney Herman Slade.
Deserted by her husband, John Madison, because he incorrectly accuses her of having an affair, Mary Madison goes to her aunt's house to have her baby, and then loses her memory in a train wreck. John, however, hears that she has died, so he takes possession of their infant daughter.
When his wife Grace inherits her father's stock, John Miller, the president of the Western Power and Development Company, becomes a millionaire and moves to New York with his family. Beset by business problems, Miller pays little attention to his wife, and Grace, feeling neglected, takes up with a bohemian set. Among her new acquaintances she meets Stuart Mordant, the attorney for Thomas Hurd, a business rival of Miller's. Grace seeks refuge from loneliness in Mordant, who makes a bargain with Hurd to gain control of her husband's company for half a million dollars.
Nora, a girl of the lower East Side of New York City, marries a rising ward politician. A child is born. They are happy, but the young politician is running for office against the old ward boss and has to be out every night. The wife becomes jealous of a certain woman. Nora's child dies. Things get worse for her as jealousy and the seeming neglect of her husband increase. She finally leaves him and becomes a model for a noted painter. The husband finds where she is, but makes no attempt to force her to return to him, though he still loves her. One of the artist's friends, a magnate in the motion picture business, promises her a chance. Her rise to stardom is quick. The climax of the story is a struggle between the old love and the new fame. She does not know that the politician has become a first-class lawyer. Finding that the old love and the new fame are not incompatible, she is reunited with her husband.
Wealthy Joshua Anson expects his son Chadwick to marry a woman of their class, but much to his chagrin Chadwick falls in love with factory girl Mary McClintock. Anson schemes to break up the romance by framing Mary in a compromising situation, but she outsmarts him and marries Chadwick. Not to be defeated, Anson offers his daughter-in-law $100,000 to divorce his son, but Mary outfoxes him once again by accepting the money, getting a divorce, and then remarrying Chadwick. Mary's last trick wins her father-in-law's respect, and he finally offers the couple his blessings.
