Sarah and Harriet have been best friends since childhood. They married at the same time, had children within the same year and now find themselves facing uncertain futures after the sudden deaths of their husbands. Though they have much in common, Sarah is a relaxed nature lover, while Harriet is intense and set in her ways. Sarah has been able to move on with her life with the help of her mother, her maid Katie and Will, the new man in her life. Harriet is unable to cope with her loss and her relationship with her daughter Pammy is strained. When Harriet is diagnosed with a serious illness, she and Sarah learn a lesson about love and friendship.
A teenage mother is forced to give up her baby for adoption and, 19 years later, when she tries to contact her son, she learns that he died, under questionable circumstances when he was three years old.
Iris is broke after her divorce and takes a job working as a housekeeper for a wealthy woman named Paula. When Paula and her husband separate, an unlikely friendship blossoms between the women.
Claire's number one priority is her family. When her husband Dennis loses his stockbroker job, the couple's traditional family roles switch. As Dennis takes on his new stay-at-home role, Claire's furniture design business takes off. Just as she's beginning to master the art of balancing her home and work life, Dennis serves her with divorce papers and charges her with being an unfit mother. Claire discovers that in a modern courtroom there are still traditional biases unsympathetic to the idea of a woman working three jobs, as a wife, an entrepreneur and a mother.
Jack, in full puberty, not only has to deal with his parents' divorce, but also feels his world is falling apart when his dad tells him he is living with a man. He slowly comes to terms with his own feelings when the girl he has a crush on turn out to have a gay dad as well and his best friend's parents end up not having the perfect marriage Jack thought they had.