The charming and still-single Joey has struck out on his own and moved to Hollywood, hoping to truly make it as an actor. After reuniting with his high-strung sister Gina, Joey moves in with Michael, his 20-year-old genius nephew, who unbelievably is literally a rocket scientist. However, what Joey lacks in book smarts he makes up for with people smarts – making him the best new friend his nephew could ask for.

Complex, offbeat Detective Charlie Crews returns to the force after serving time in prison for a crime he didn’t commit. Crews’ new lease on life has provided him with a Zen-like outlook, peace of mind and no need for vengeance, an attitude which can be challenging to maintain when someone he cares about is threatened — or when he is investigating the mystery surrounding the murder he was falsely accused of.

Stef Foster, a dedicated police officer, and her partner Lena Adams, a school vice principal, have built a close-knit, loving family with Stef's biological son from a previous marriage, Brandon, and their adopted twins, Mariana and Jesus. Their lives are disrupted in unexpected ways when Lena meets Callie, a hardened teen with an abusive past who has spent her life in and out of foster homes. Lena and Stef welcome Callie and her brother, Jude, into their home thinking it's just for a few weeks, until a more permanent placement can be found. But life has something else in store for the Fosters.

The close-knit Walker family deals with struggles and triumphs.

Obstetrician/gynecologist Mindy Lahiri tries to balance her personal and professional life, surrounded by quirky co-workers in a small medical practice in New York City.

CSI: Miami follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.

A British husband-and-wife comedy writing team travel to Hollywood to remake their successful British TV series, with disastrous results.

Follows the lives and families of three adults living and growing up in the United States of America in present and past times. As their paths cross and their life stories intertwine in curious ways, we find that several of them share the same birthday - and so much more than anyone would expect.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

The nicest guy in the Midwest moves his family into a tough neighborhood in Los Angeles where not everyone appreciates his extreme neighborliness. That includes their new next-door neighbor Calvin.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

From murder and espionage to terrorism and stolen submarines, a team of special agents investigates any crime that has a shred of evidence connected to Navy and Marine Corps personnel, regardless of rank or position.

Looking down on her friends and family isn't a way of life for Mary Alice Young... it's a way of death. One day, in her perfect house, in the loveliest of suburbs, Mary Alice ended it all. Now she's taking us into the lives of her family, friends and neighbors, commenting from her elevated P.O.V.

Dexter Morgan, a blood spatter pattern analyst for the Miami Metro Police also leads a secret life as a serial killer, hunting down criminals who have slipped through the cracks of justice.

The series follows the ventures of a Missing Persons Unit of the FBI in New York City.

A single-camera ensemble comedy following the lives of an eclectic group of detectives in a New York precinct, including one slacker who is forced to shape up when he gets a new boss.

The lives of staff in the womens' health clinic of a fictitious hospital in Philadelphia.

Rules of Engagement is a comedy about the different phases of male/female relationships, as seen through the eyes of a newly engaged couple, Adam and Jennifer, a long-time married pair, Jeff and Audrey, and a single guy on the prowl, Russell. As they find out, the often confusing stages of a relationship can seem like being on a roller coaster. People can describe the ride to you, but to really know what it's like you have to experience it for yourself.

Pepper Dennis is a reporter hoping to move into the anchor chair. She may or may not have helped her career ambitions by having a one-night stand with the guy who turns out to be her new boss.

A workplace comedy centered on Kevin, a young man who declares his unrequited love for his coworker Audrey in a letter, believing he’ll never see her again after he accepts a job overseas. But when the opportunity falls through and Kevin is forced to return to his old job, how will he and Audrey continue to work together now that his feelings are no longer secret?

A gifted young teen tries to survive life with his dimwitted, dysfunctional family.

A team of dedicated amateurs work on cases involving unidentified victims. After the police have given up, this group must first solve the puzzle of the victim's identity in order to then help catch the killer. They work to give the deceased back their names, lest they become—The Forgotten.

Chicagoan Frank Gallagher is the proud single dad of six smart, industrious, independent kids, who without him would be... perhaps better off. When Frank's not at the bar spending what little money they have, he's passed out on the floor. But the kids have found ways to grow up in spite of him. They may not be like any family you know, but they make no apologies for being exactly who they are.

Principal Steven Harper runs Winslow High School as best as he can while dealing with the demands of the faculty, the students and their parents.

The exploits of the Los Angeles–based Office of Special Projects (OSP), an elite division of the Naval Criminal Investigative Service that specializes in undercover assignments.