Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.

Bored and unhappy as the Lord of Hell, Lucifer Morningstar abandoned his throne and retired to Los Angeles, where he has teamed up with LAPD detective Chloe Decker to take down criminals. But the longer he's away from the underworld, the greater the threat that the worst of humanity could escape.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

Mick St. John is a captivating, charming and immortal private investigator from Los Angeles, who defies the traditional blood-sucking norms of his vampire tendencies by using his wit and powerful supernatural abilities to help the living.

Jesse Warner is a 26-year-old single mother juggling between her job, her dreams and her family responsibilities.

Down on his luck and out of money, former R&B star Steve Hightower lands a music teacher gig at an inner-city Chicago school. Showing who's in charge with his unorthodox approach, Steve discovers a new groove at Washington High School.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

Six young people from New York City, on their own and struggling to survive in the real world, find the companionship, comfort and support they get from each other to be the perfect antidote to the pressures of life.

Into every generation a slayer is born: one girl in all the world, a chosen one. She alone will wield the strength and skill to fight the vampires, demons, and the forces of darkness; to stop the spread of their evil and the swell of their number. She is the Slayer.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

Miracles follows Paul Callan, an investigator of modern miracles for the Catholic Church who questions his faith after repeatedly finding mundane explanations for various supposed phenomena. After he witnesses a true, supernatural miracle that saves his life, only for his findings to be dismissed on a lack of evidence, Paul leaves behind the Church and is approached by Alva Keel to join his organization Sodalitas Quaerito, investigating and cataloguing "unexplainable" phenomena. Along with former police officer Evelyn Santos, Paul and Alva attempt to battle the impending "darkness" before it's too late.

A team of dedicated amateurs work on cases involving unidentified victims. After the police have given up, this group must first solve the puzzle of the victim's identity in order to then help catch the killer. They work to give the deceased back their names, lest they become—The Forgotten.