The Pritchett-Dunphy-Tucker clan is a wonderfully large and blended family. They give us an honest and often hilarious look into the sometimes warm, sometimes twisted, embrace of the modern family.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Patrick Jane, a former celebrity psychic medium, uses his razor sharp skills of observation and expertise at "reading" people to solve serious crimes with the California Bureau of Investigation.

Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.

Jules balances her life of being a college student, while serving up vigilante justice on her school's campus. Until Ophelia, a computer hacker, discovers her secret and entangles herself in Jules' quest for vengeance.

After many years spent at the “Cheers” bar, Frasier moves back home to Seattle to work as a radio psychiatrist after his policeman father gets shot in the hip on duty.

From murder and espionage to terrorism and stolen submarines, a team of special agents investigates any crime that has a shred of evidence connected to Navy and Marine Corps personnel, regardless of rank or position.

Eccentric genius Walter O’Brien and his team of brilliant misfits comprise the last line of defense against complex, high-tech threats of the modern age. As Homeland Security’s new think tank, O’Brien’s “Scorpion” team includes Toby Curtis, an expert behaviorist who can read anyone; Happy Quinn, a mechanical prodigy; and Sylvester Dodd, a statistics guru.

The charming and still-single Joey has struck out on his own and moved to Hollywood, hoping to truly make it as an actor. After reuniting with his high-strung sister Gina, Joey moves in with Michael, his 20-year-old genius nephew, who unbelievably is literally a rocket scientist. However, what Joey lacks in book smarts he makes up for with people smarts – making him the best new friend his nephew could ask for.

Samantha Newly has been a bad, bad girl. But thanks to an 8-day coma, she can't remember a thing. Fortunately her best friend Andrea is by her side with a cocktail and the 4-1-1 on every dirty deed. But the more Sam pieces together her past, the less she likes her old self. Maybe this is a chance to start over and do it all again.

Follows the personal and professional lives of a group of doctors at Seattle’s Grey Sloan Memorial Hospital.

In the unreal world of Sacred Heart Hospital, John "J.D." Dorian learns the ways of medicine, friendship and life.

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

The early life of child genius Sheldon Cooper, later seen in The Big Bang Theory.

A five-person team comprised of a thief, a grifter, a hacker, and a retrieval specialist, led by former insurance investigator Nathan Ford, use their skills to fight corporate and governmental injustices inflicted on ordinary citizens.

Set in 1960-1970 New York, this sexy, stylized and provocative drama follows the lives of the ruthlessly competitive men and women of Madison Avenue advertising.

Four egocentric friends run a neighborhood Irish pub in Philadelphia and try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.

Steve McGarrett returns home to Oahu, in order to find his father's killer. The governor offers him the chance to run his own task force (Five-0). Steve's team is joined by Chin Ho Kelly, Danny "Danno" Williams, and Kono Kalakaua.

The exploits of the Los Angeles–based Office of Special Projects (OSP), an elite division of the Naval Criminal Investigative Service that specializes in undercover assignments.