The Weekenders is a Disney animated series about the weekend life of four diverse 7th graders: Tino Tonitini, Lorraine McQuarrie, Carver Descartes, and Petratishkovna Katsufrakis, voiced by veteran cartoon voice-actors: Jason Marsden, Grey DeLisle, Phil LaMarr, and Kath Soucie, respectively. It is stated at least once that the four main characters are each twelve years old. The setting is the fictional town of Bahia Bay, California. The show was created by Doug Langdale, later creator of Disney Channel's Dave the Barbarian.

Families, friends, enemies and lovers experience life-changing events in the large upstate New York city of Port Charles, which has a busy hospital, upscale hotel, cozy diner and dangerous waterfront frequented by the criminal underworld.