65 million years ago, the knights of the Ryusoul Tribe were selected to participate in a war campaign against the dictating Druidon Tribe who sought to rule Earth. But the Druidon's war campaign was halted by the meteor that brought the age of the dinosaurs to an end, forcing them to flee into space. Meanwhile, the Kishiryu were placed in a deep sleep as a failsafe should the Druidon return. The chosen knights choose to live in peace while passing their mantle down across generations. In the present day, the Druidon return to reclaim Earth as the current generation of knights, the Ryusoulgers, battle them with the support of Ui Tatsui and her father Naohisa Tatsui.

During turbulent economic times in Japan, Masahiko Washizu leads a foreign investment fund and is criticized for being a vulture. He tries to buy a bank and another company that are experiencing financial depression.

Two detectives communicate through a walkie-talkie to solve a cold case. One detective exists in the present day, and the other detective exists 15 years in the past.

Inami and Tamaru work at the Public Security Mobile Investigation Unit Special Investigation Team, a team made up of specialists with different expertise. Inami tackles criminals with showy maneuvers, while Tamaru corners criminals with cool calculation. Together, the team tackles terrorists, new religious cults, military spies, secret narcotics organisations and complicit politicians.

Maki Maki, Sebuki Suzume, Beppu Tsukasa and Iemori Yutaka happen to meet and form a quartet. They even begin to live together in Karuizawa during the winter, but there is a big hidden secret.

This work is a human drama that attorney, Taku Kurokawa challenges reversal play with weapons, passion, and science as a weapon to cause "miracle" to clear false charges. Kurokawa who plays Sakaguchi actively opposes fake crime defense, which is said to be impossible, reproduces the events that occurred on the scene in an experiment and tries to elucidate the incident. In addition, Naoki Fujiki appears as a new American lawyer, Kazuaki Wakakura who is swayed by the pioneer, Haruna Kawaguchi , a scientist who lends power to Taku, Kyoichiro Akiro .

The Makai fight a secret war against the demon forces known as Horrors, evil creatures that manifest themselves through darkness to devour Humanity. On the frontlines are the Makai Knights, given the task of watching over a district and eliminating any Horrors that manifest there. GARO follows the tales of the Knights bearing the title of ‘Golden Knight Garo’, and their duty to vanquish the Horrors and protect Humanity from the darkness.