Ten years have passed, and Sidney Prescott has put herself back together thanks to her writing. However, her return to Woodsboro sparks the return of the Ghostface Killer.

Publisher Will Atenton quits a lucrative job in New York to relocate his wife, Libby, and their daughters to a quaint town in New England. However, as they settle into their home the Atentons discover that a woman and her children were murdered there, and the surviving husband is the town's prime suspect. With help from a neighbor who was close to the murdered family, Will pieces together a horrifying chain of events.