Maria is a girl in her early teens whose family lives in an upscale gated suburb. Maria's parents are going out of town for a week, and rather than leave her with relatives or hire a babysitter, Maria is put in charge of looking after her little sister Sofia, with housekeeper Esther serving as a nominal adult authority figure, though for the most part she lets Maria and the others do what they please. With only their parents bedroom off-limits, Maria and Sofia have the run of the house, and soon they and their friends Facundo, Quique, Rodrigo and Timmy are spending their days exploring the place. As the kids begin creating their own rules to run counter to the ones their absent parents set down, Esther brings a young relative, Fernando, to play with them, and the privileged kids begin to get a notion of the ways of the outside world.
The godmother and Perla are the world to "the little girl," a world defined by the four walls of a studio apartment with one window looking nowhere. Only space and alter the monotony, the blood transfusion sessions to which must be submitted Pearl and almost anonymous sexual encounters of the baby.
The series revolves around Gabo, a soccer-loving teenager who, upon receiving a scholarship from the prestigious Sports Academic Institute (IAD) of Buenos Aires, will see his dream of playing at Los Halcones Dorados, the renowned amateur team of the school, and also his longing to become a professional footballer.
A scientist dies in mysterious circumstances while performing an investigation into a tannery in Corrientes. Her husband and his best friend (who was a lover of women) travel to the place to discover what had happened, and end up getting into an issue that threatens their lives.