Counselors are being killed off at summer camp, and Sam is stuck in the middle of it. Instead of contacting the cops, he calls his friend and slasher-film expert Chuck to discuss his options.
After visiting her father's grave, Lilly and her mother are involved in a terrible car accident leaving Lilly orphaned and unable to see. In her youth, she struggles with her blindness and begins to hear voices. Unbeknownst to her they don't belong to the living. After years of learning to cope, Lilly is now happily married with a baby on the way. Lilly soon discovers her unborn baby has become a vessel a second chance for souls stuck in limbo to be re-born. She only has until the baby's first heartbeat to decide which soul will be re-born through her. Now the voices she heard in her youth have returned, clamoring for the chance to come back. Among the voices, she befriends the spirit of a little girl tied to a years-old cold case. Lilly finds herself in a desperate struggle with the girl's murderers and the souls vying to be born again.
Before Sam and Dean, there was John and Mary. Told from the perspective of narrator Dean Winchester, this is the epic, untold love story of how John met Mary, and how they put it all on the line to not only save their love, but the entire world.