Talented and successful surgeon Daniel Milton has his world shattered when his wife Beth develops a fatal degenerative disease. After conventional treatment options run out, Daniel partners with the lonely yet resourceful Lee to start a literal Underground clinic in the vast network of tunnels beneath Temple Tube Station in London.
In 17th century England, Mary Villiers molds her beautiful son, George, to seduce King James I, intending to gain riches and influence through outrageous schemes.
The genre-bending novel, part love story, part spy thriller, follows Tom (Cumberbatch), a seemingly-ordinary man who suffers from a very rare condition called anageria, which has kept him alive for centuries. Throughout history, Tom and men and women like him, have been feared, misunderstood and persecuted. Their lives are one of perpetual loss, as they see family, friends, lovers and children die before them. To survive, those with anageria have formed a secret society to protect their own, but also to enforce strict rules of behavior. The first rule, and the one Tom threatens to break: never fall in love.
