Two very different families live in the village of Santa Lucía who are involved in a whirlwind of passion, pain, and revenge. The rivaling families are the Mendozas and the Alcocers. Severiano Mendoza and Candela Santana are a rich and powerful marriage who live at the ranch, "Las Ánimas", along with their young son, Cristóbal. Roberta and Raymundo Alcocer also have a daughter named Alonza; however, they do not live with the same luxuries as the Mendoza family, which causes frustration and resentment in Roberta as nothing is enough to fill the inferiority complex that follows her like a shadow.

The main theme of the series tells the story about private lives of a group of women who are frequent clients of “Angelica Style”, a prestigious beauty clinic. This group of women, Angelica, Nora, Mercedes, Samantha, Loreto, Vanesa, Lilí, Gabriela, Fernanda and Cecilia, have one thing in common: they have all failed to find the men of their dreams. As the stories blend, their different personalities are shown and their deepest wishes are revealed. They want to find a man who can understand them with freedom and love.