Five ordinary people with superhuman physical and mental abilities are brought together to form one extraordinary team of Alphas. Operating within the U.S. Department of Defense, the team investigates cases that point to others with Alpha abilities.

As a young associate, Mitchell McDeere brought down the prestigious Memphis law firm of Bendini, Lambert & Locke, which operated as a front for the Chicago mob—and his life was never the same. After a difficult decade, which included a stay in the Federal Witness Protection program, Mitch and his family now emerge from isolation to reclaim their lives and their future—only to find that past dangers are still lurking and new threats are everywhere.

Constable Benton Fraser, an officer of the Royal Canadian Mounted Police, is attached to the Canadian consulate but works with Chicago Police Department to solve crimes.