When Iori Kitahara heads off to college, he decides to live at his uncle's dive shop in Izu named Grand Blue. Iori is looking forward to experiencing college life amidst the roar of the waves, the blazing sun, and his cute cousin who lives with him! However, Iori runs into a group of tough guys playing strip rock-paper-scissors, and ends up joining Peek-a-Boo, the college's diving club!

First-year high schooler Midori Asakusa loves anime so much, she insists that "concept is everything" in animation. While she spends her time doodling endless ideas and settings in her sketchbook, she hasn't taken the first step to creating anime, insisting that she can't do it alone. After Asakusa's money-loving best friend Sayaka Kanamori notices her genius and drive – and when it becomes clear that their classmate and charismatic fashion model Tsubame Mizusaki wants to be an animator – the energetic trio start an animation club. Together, the three aim to realize the "ultimate world" that exists in their minds, as they come to see the power that fiction and imagination have on their lives and the world around them.

Makoto 'Smile' Tsukimoto and his friend Yutaka 'Peco' Hoshino have been playing table tennis together since they were kids, but as they enter high school, they find that the game, and how they see it, has changed. Peco, brimming with confidence and energy, wants to be the best in the world, but the reserved Smile has little fighting spirit and doesn't want to sacrifice others' happiness just to win, despite his innate talent. As the two grow, and experience the ups and downs of the sport – and life – they try to figure out exactly who they really are and what drives them to play.

For Himuro, being a descendant of a snow spirit is tough at the workplace when your emotions can lead to snow blasts with snowmen and igloos. Any emotionally charged incident with coworkers can trigger it—conflict, fun, and in this case, romance. And with his lovely and calm coworker Fuyutsuki, he gets more frozen, literally. Get ready for a snow-white office romance that blows in like a blizzard.

Kiyotaka Ayanokoji has just enrolled at Tokyo Koudo Ikusei Senior High School, where it's said that 100% of students go on to college or find employment. But he ends up in Class 1-D, which is full of all the school's problem children. What's more, every month, the school awards students points with a cash value of 100,000 yen, and the classes employ a laissez-faire policy in which talking, sleeping, and even sabotage are permitted during class. One month later, Ayanokoji, Horikita, and the students of Class D learn the truth of the system in place within their school...

Takumi Harada is an extremely gifted baseball pitcher. Upon entering junior high school, Takumi moves to a town situated in the mountains due to his father's job transfer. There, he meets a new classmate Go Nagakura, a catcher who is able to get Takumi's most powerful pitches. Takumi and Go both join the school's baseball team where they develop a firm friendship and grow as individuals through their battery.

The students of Class 3-E have a mission: kill their teacher before graduation. He has already destroyed the moon, and has promised to destroy the Earth if he can not be killed within a year. But how can this class of misfits kill a tentacled monster, capable of reaching Mach 20 speed, who may be the best teacher any of them have ever had?

In this story, the world is in chaos, thanks to Washu. Now in order to save it, Tenchi Masaki must go undercover as a student teacher at an all-girls school. Unfortunately for him, trouble always comes his way as he has a hard time dealing with the hijinks of his new students.

Ryuto Kashima is the school's gloomy introvert, and he's got a crush on Runa Shirakawa, the popular girl. After losing a bet to classmates, he confesses his feelings to Runa one day. Shocked and secretly just as inexperienced as Ryuto, Runa agrees to date him. The relationship grows between two people who are as similar as they are different. Will their young love blossom? Time will tell!

Tsumiki Miniwa, a small girl who packs a punch, is in love with her best friend, tall and easygoing Io Otonashi. The only problem is that she can't bring herself to come out and say it. And, despite the fact that he can otherwise read her like a book, Io doesn't seem to be able to pick up the obvious clues—even with all of their friends teasing that there's no one better suited for each other. Acchi Kocchi follows Tsumiki and her circle of friends as they go through their day-to-day lives. Between Mayoi the electronics nerd, Sakaki the good-natured prankster, and the nosebleed-prone Hime, Tsumiki's friends will never let her live down her crush. But only time will tell if Tsumiki will gain the courage to finally say how she truly feels.

First year high school student and occultist, Nene Yashiro summons "Hanako-san of the Toilet" to grant her romantic wishes. She ends up Hanako's spiritual assistant, helping him destroy supernatural beings and change rumors to balance the spirit and human worlds. Along the way, Nene learns about her connection to the spirit world and the dark secrets regarding Hanako's past.