Five ordinary people with superhuman physical and mental abilities are brought together to form one extraordinary team of Alphas. Operating within the U.S. Department of Defense, the team investigates cases that point to others with Alpha abilities.

A young CIA operative, Annie Walker, is mysteriously summoned to headquarters for duty as a field operative. While Annie believes she's been promoted for her exceptional linguistic skills, there may be something or someone from her past that her CIA bosses are really after. Auggie Anderson is a CIA military intelligence agent who was blinded while on assignment and is Annie's guide in this world of bureaucracy, excitement and intrigue.