The adventures of relatable and adventurous Riley Matthews, the tween daughter of Cory and Topanga Matthews, and her bold best friend Maya as they traverse the twists and turns of teenage years at Manhattan's John Quincy Adams Middle School where Riley's dad is their History teacher.

A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.