During a trip to Sicily in 1920, Luigi Pirandello meets two gravediggers-turned-playwrights rehearsing a play with their amateur dramatics. Pirandello takes an interest in the odd couple, having been suffering from writer's block while working on his eventual masterpiece, Six Characters in Search of an Author.
Originally polar opposites, an American fashion student and the daughter of an industry mogul form an everlasting bond and start a rock band in Milan, Italy.