A young Polish partisan flees from the Warsaw Uprising. Whilst hiding in the yard of a countryside manor, he is chased up a tree by a large wolfhound. With his rifle out of reach, there seems to be no way to escape his predicament.
After years of being sheltered from the human world, the Turtle brothers set out to win the hearts of New Yorkers and be accepted as normal teenagers through heroic acts. Their new friend April O'Neil helps them take on a mysterious crime syndicate, but they soon get in over their heads when an army of mutants is unleashed upon them.
Amid the stark discord of twin cities Piltover and Zaun, two sisters fight on rival sides of a war between magic technologies and clashing convictions.