The Fugitive Task Force relentlessly tracks and captures the notorious criminals on the Bureau's Most Wanted list. Seasoned agents oversee the highly skilled team that functions as a mobile undercover unit that is always out in the field, pursuing those who are most desperate to elude justice.

Regina Haywood is the newly promoted deputy inspector of East New York, a working-class neighborhood at the edge of Brooklyn. She leads a diverse group of officers and detectives, some of whom are reluctant to deploy her creative methods of serving and protecting in the midst of social upheaval and the early seeds of gentrification.