Fenwick and Moriarty's other henchmen assume disguises, using technology invented by Dr. Blessington to make their DNA unrecognizable.

Jason Gray-Stanford
Sherlock Holmes (voice)

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Akiko Morison
Inspector Beth Lestrade (voice)

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John Payne
Dr. John Watson (voice)

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Richard Newman
Professor James Moriarty (voice)

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William Samples
Chief Inspector Greyson (voice)

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Ian James Corlett
Martin Fenwick (voice)

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Viv Leacock
Wiggins (voice)

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Jennifer Copping
Deidre (voice)

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Gillian Barber
(voice)

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Kathleen Barr
(voice)

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