After discovering that a patient's family might have been abusive, Dr. Choi and April contemplate calling child services. Dr. Manning and Dr. Halstead struggle to see eye to eye in guiding a family who is dealing with their premature baby. Dr. Rhodes is persuaded into preforming a risky surgery on Dr. Bekker's mentor. Meanwhile, Dr. Reese joins Dr. Charles on a visit to the Cook County jail.

Nick Gehlfuss
Dr. Will Halstead

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Marlyne Barrett
Maggie Lockwood

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Yaya DaCosta
April Sexton

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S. Epatha Merkerson
Sharon Goodwin

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Torrey DeVitto
Dr. Natalie Manning

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Oliver Platt
Dr. Daniel Charles

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Rachel DiPillo
Dr. Sarah Reese

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Colin Donnell
Dr. Connor Rhodes

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Brian Tee
Dr. Ethan Choi

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Norma Kuhling
Dr. Ava Bekker

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Guest stars